When Jess finally receives the long-awaited organ transplant that she desperately needs to live, she believes all her troubles are behind her. That is until she starts developing some interesting side effects from the transplant-a newfound set of fantastical abilities and superpowers. When she discovers that everyone else who received organs from this donor is also experiencing the same thing, they must all figure out who this donor was, and decide what to do with the powers-use them for good, evil, or simply ignore them altogether.